How is D9 THCP Made?

green leaves in close up photography

D9 THCP is a newly discovered cannabinoid found in extremely low quantities in some cannabis strains and can be made in a laboratory by modifying legal hemp-derived CBD. Italian experts accidentally discovered it in 2019 while analyzing a specific cannabis strain. THCP’s full name is delta-9-tetrahydrocannabiphorol, which is commonly abbreviated as delta-9 THCP.

So far, THCP is the highest potent THC analog. This THC analog is really promising for all cannabis enthusiasts. In recent years, there has been no shortage of THC analogs. Alternatives to delta 9 THC, such as delta 10 THC and delta 8 THC, has piqued the public’s curiosity. However, there is now a more potent alternative known as THCP. So keep reading to find out what it is and how it is made.

What Is D9 THCP?

THCP is a newly discovered, naturally occurring THC analog. The main distinction between THCP and THC is that THCP has 2 extra carbons in its chemical composition. Delta 9 THC has 5 carbons on its alkyl side chain. On the other hand, THCP has 7 carbons on its alkyl side chain. Simply put, THCP is stronger than Delta 9 THC. With a smaller dose, it may make you feel extremely high.

Although UNIHEMP research discovered this compound in 2019, many believe it has existed for a long time. Furthermore, many claims that this is why some marijuana strains are far more potent than others, despite having the same or less THC content.

The UNIHEMP research team not only discovered THCP by chance but also discovered CBDP while studying the chemical profile of the FM2 strain. THCP has piqued the interest of experts because it is believed to have 33 times higher binding affinity than THC.

How is D9 THCP Made


Almost all cannabinoids found in cannabis and hemp plants, including D9 THCP, THC, and CBD, start as CBGA. CBGA undergoes an enzymatic interaction with other acidic chemicals in cannabis to produce tetrahydrocannabiphorolic acid (THCPA), a precursor molecule for THCP. The cannabis or hemp plant then progressively converts THCPA to THCP via a procedure known as decarboxylation.

To obtain a cannabinoid-rich fraction of FM2, n-hexane is utilized to extract the raw material rather than ethanol, which contains additional pollutants such as flavonoids and chlorophylls in addition to cannabinoids. To obtain a pure cannabinoid extract, a further dewaxing process at –20°C for 48 hours and removal of the precipitated wax is required.

Semi-preparative liquid chromatography using a C18 stationary phase separated 80 fractions, which were then studied using LC-HRMS. As a result, the fractions containing primarily tetrahydrocannabipgorolic acid (THCPA) were separately heated at 120 °C for 2 hours to obtain its corresponding neutral counterpart D9 THCP as clear oil with up to 95 percent purity.


Due to the low quantity of D9 THCP in cannabis, chemists produce D9 THCP artificially in labs to meet the rising demand. In 2019, the first study describing THCP extraction from a cannabis plant was published, and it was later modified to establish the present production technology. Because CBD is utilized as a beginning ingredient to manufacture D9 THCP, it can be derived from hemp.

Is D9 THCP Safe?

It’s natural to be anxious about a product’s safety when you try something new. There hasn’t been enough research done on THCP to know if it’s fully safe. However, there is no evidence that it is more harmful than other THC analogs. THCP has the same effect on the body as THC, but it is more potent. Early results also suggest that when consumed at the same dose, THCP has the same level of safety.

To avoid any negative side impacts, however, consume small doses of THCP. Start with a 0.3mg dose if you’re a beginner. Anything more may result in an unpleasant high. THC analogs with long tails have been discovered to have more hazardous side effects than THC. As a result, THCP may cause more unfavorable side effects. However, data is equivocal.

Does D9 THCP Show Up on a Drug Test?

Every cannabis consumer’s biggest nightmare is a drug test. Some businesses may fire their employees if cannabis is discovered with them. Specialists are unsure whether THCP stays in your system longer due to no research on the compound. For the time being, it is wise to contrast THCP with all other THC analogs. Consider how long Delta 9 THC holds in your system:

THC can be detected in your urine up to 30 days after your last usage. However, it is heavily dependent on how much you consume. A urine test can reveal average cannabis consumption 5 to 7 days after your last dosage, frequent cannabis uses 15 days following your last dose and chronic cannabis use up to 30 days after the last dose. As a result, it’s best to stop taking D9 THCP 30 days before a drug test.

You can flush cannabis from your system using a variety of approaches. Detox kits, detox drinks, creatine supplements, and activated charcoal products are among them. Staying hydrated might also help drain THCP out of your system. If you drink too much water, you may produce a strange result. But that’s when creatine comes in handy to mask overhydration.


D9 THCP is a naturally occurring powerful cannabinoid in cannabis that can also be synthesized artificially in laboratories by professional chemists utilizing hemp-derived CBD. A comprehensive study on THCP is still needed. However, a preliminary study indicates that it is a superior, more powerful alternative to delta 8 THC, delta 9 THC, and delta 10 THC. If you want to experiment with THCP, start with a low dose.

Although the effects might be extremely pleasurable, it is possible to overdose on THCP. Begin with a 0.3mg dose and gradually increase. THCP is expensive and difficult to find in 2022, particularly outside the United States. However, State of Mind Labs is here to help. Whatever your requirements are, contact State of Mind Labs or place your order on the website store; your order will be delivered safely. Click here to learn more about D9 THCP!